Although more commonly a surname, Irby is also a given name. Notable people with the surname include:

Irby Brown (1928—2016), American painter Irby Curry (1894–1918), American football quarterback Irby Koffman (1899–1968), American football coach

Edith Irby Jones (1927–2019), American physician Francis Irby Gwaltney (1921–1981), American author George Irby Redditt (1863–1953), Democratic member of the Mississippi House of Representatives

See also Irby (surname) for people with the surname Irby