A ghretropin is a substance, usually a peptide, that increases the secretion of the "hunger hormone" ghrelin when consumed. Ghretropins that work on mice have been reported in the enzymatic digests of wheat, rice, and soy bean proteins. When a mouse consumes a purified version of the peptide, its plasma concentration of ghrelin and food intake increase. If they also work on humans, they may represent a way to boost the appetite of elderly and anorexic people.
List of ghretropins Name Sequence Year discovered Effective in Soy-ghretropin NKNPFLFGSNR 2016 Mice (MGN3-1 cell culture, oral) Wheat ghretropin A SQQQQPVLPQQPSF 2021 Mice (MGN3-1 cell culture, oral) Wheat ghretropin B LSVTSPQQVSY 2021 Mice (MGN3-1 cell culture) Wheat ghretropin C YPTSL 2021 Mice (MGN3-1 cell culture) Rice ghretropin A QAFEPIRSV 2022 Mice (MGN3-1 cell culture, oral) Rice ghretropin B TNPWHSPRQGSF 2022 Mice (MGN3-1 cell culture, oral)
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