Kelly's is a test statistic that can be used to test a genetic region for deviations from the neutral model, based on the squared correlation of allelic identity between loci.
Details Given loci and , the Linkage Disequilibrium between these loci, is denoted as
where is the frequency of the alternative allele at i and j co-occurring and and the frequency of the alternative allele at and respectively.
a standardised measure of this is the squared correlation of allelic identity between loci and
Where averages over all pairwise combinations between S loci.
Usage Inflated scores indicate a deviation from the neutral model and can be used as a potential signature of previous selection
References