The Rivière de Cayenne (, "Cayenne River") is a river in French Guiana, formed by the Rivière des Cascades, Tonnegrande, and Montsinéry River. It flows into the Atlantic Ocean near the city of Cayenne, forming an estuary about 2 km long. It is long, including its upper course Rivière des Cascades.
The river featured prominently in both the movie and the book Papillon by Henri Charrière.
See also List of rivers of French Guiana List of rivers of the Americas by coastline
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