The surname Labine may refer to:
Claire Labine (1934–2016), U.S. soap opera writer Clem Labine (1926–2007), U.S. baseball player Eleanor Labine, American TV writer Gilbert Labine (1890–1977), Canadian prospector Kyle Labine (born 1983), Canadian actor Leonard Gerald Labine (1931–2005), Canadian ice hockey player Marcel Labine (1948–2026), Canadian poet Matthew Labine (1959–2017), American soap opera writer Robert Labine (1940–2021), Canadian politician Tyler Labine (born 1978), Canadian actor and comedian