110th Street may refer to:
Streets 110th Street (Manhattan), a major east–west street in Manhattan, New York City
Stations Cathedral Parkway–110th Street station (IRT Broadway–Seventh Avenue Line), serving the train Cathedral Parkway–110th Street station (IND Eighth Avenue Line), serving the trains 110th Street–Malcolm X Plaza station, serving the trains 110th Street station (IRT Lexington Avenue Line), serving the trains 110th Street station (IRT Ninth Avenue Line), former station
See also Across 110th Street, a 1972 American action-crime film "Across 110th Street" (song), a song by Bobby Womack from the soundtrack and film of the same name