KSD may refer to:

Radio and television stations KSD (FM), a radio station in St. Louis, Missouri, U.S. KSD, former callsign for KTRS (AM), a radio station in St. Louis, Missouri, U.S. KSD-TV, former callsign for KSDK, a television station in St. Louis, Missouri, U.S.

Education India KSD Shanbhag Vidyalaya, a school in Satara, Maharashtra

United States Kansas State School for the Deaf, Olathe Keeneyville School District 20, Hanover Park, Illinois Kentucky School for the Deaf, Danville

Other uses Tolai language (ISO 639:ksd), Papua New Guinea Karlstad Airport (IATA airport code), Sweden Koninklijke Stichting Defensiemusea (Royal Foundation for Defence Museums), the Netherlands Korea Securities Depository KSD-64, an NSA-developed memory chip KSD-1, a WWII US air-to-surface missile Kadanuumuu (KSD-VP-1/1), an Australopithecus afarensis fossil discovered in Afar