Highland Creek may refer to:
Rivers Ontario, Canada Highland Creek (Toronto), in Scarborough, which flows into Lake Ontario Highland Creek, in Kenora and Rainy River districts, a tributary of the Little Turtle River Highland Creek, in Lambton County, which flows into Lake Huron Highland Creek, in Renfrew County, a tributary of the Madawaska River (Ontario) United States Highland Creek, a tributary of the Rubicon River (California)
Settlements Highland Creek, Toronto, in Ontario, Canada Highland Creek (Charlotte neighborhood), a large subdivision in southern North Carolina, United States.