Assaf may refer to:
Assaf (name), a given name and surname Assaf (sheep), a breed from Israel Academy of Science of South Africa (ASSAf) The Book of Assaf, the earliest medical book written in Hebrew (a misspelling of The Book of Asaph) Operation Assaf, an Israeli operation during the 1948 Arab-Israeli War
See also Saint Asaph (died 601), Welsh Roman Catholic saint and bishop Asaf, includes a list of people with the name