Osama or Usama may refer to:
People Osama (name), an Arabic given name Osama bin Laden (1957–2011), Saudi Arabia-born Islamist dissident and militant leader who founded al-Qaeda Ōsama (born 1960), Japanese musician
Film Osama (film), a 2003 film made in Afghanistan Being Osama, a 2004 documentary film of six men named Osama
Other uses "Osama" (song), a 2021 single by Zakes Bantwini Dinner With Osama, a 2008 collection of short stories by Marilyn Krysl Osama (novel), a 2011 World Fantasy Award-winning novel by Lavie Tidhar
See also Obama (disambiguation) Ōsama Game, a Japanese 2011 horror film Osamu