PAE may refer to:

Science and technology Predicted Aligned Error, AlphaFold output file format for errors of protein structure prediction Physical Address Extension, an x86 computer processor feature for accessing more than 4 gigabytes of RAM Power added efficiency, a percentage that rates the efficiency of a power amplifier Post Antibiotic Effect, the period of time following removal of an antibiotic drug during which there is no growth of the target organism Port Access Entity, in the IEEE 802.1X networking environment Primary amoebic encephalitis, another name for primary amoebic meningoencephalitis Prostatic artery embolization, a treatment for benign prostatic hyperplasia

Places City of Port Adelaide Enfield, South Australia Paine Field (IATA airport code), an airport in Everett, Washington

Other uses Pacific Architects and Engineers, a United States defense contractor Post-autistic economics, a criticism of neoclassical economics Provisional Admission Exercise, an interim exercise/period in Singapore education Patent assertion entity, a patent troll company

See also Large Physical Address Extension (LPAE), in the ARM architecture