Puyo may refer to:
Puyo, Pastaza, the capital of Pastaza, a province in Ecuador Buyeo or Puyŏ, an ancient Korean kingdom Buyeo County, in South Korea Puyo (manga artist), a Japanese manga artist Puyo Puyo, a Japanese video game series Puyo, Su-ngai Kolok, Narathiwat Province, Thailand Apostolic Vicariate of Puyo, of the Roman Catholic Church, in Ecuador Inés Puyó (1906–1996), Chilean painter