Shchedrin (Щедрин) is a Russian surname. Notable people with the surname include:

Grigori Shchedrin (1912–1995), Soviet submariner Mikhail Saltykov-Shchedrin (1826–1889), Russian writer Rodion Shchedrin (1932–2025), Soviet and Russian composer and pianist Semyon Shchedrin (1745–1804), Russian painter Sylvester Shchedrin (1791–1830), Russian painter

See also Shchadryn, an agrotown in Gomel Region, Belarus 4625 Shchedrin, an asteroid