EME may refer to:

Companies and organizations Edison Mission Energy, a defunct American power company Emcor, an American construction company College of Electrical and Mechanical Engineering, a constituent college of National University of Sciences and Technology, Pakistan Corps of Royal Canadian Electrical and Mechanical Engineers, of the Canadian Forces Indian Army Corps of EME, of Electronics and Mechanical Engineers Pakistan Army Corps of Electrical and Mechanical Engineering

Science ECB-mask-ECB, a block cipher mode of operation used for disk encryption EME (psychedelic), a drug Early myoclonic encephalopathy Earth–Moon–Earth communication Eigenmode expansion Electromagnetic environment Electromembrane extraction Early Medieval Europe (journal) Encrypted Media Extensions

Language Early Modern English, a phase of the English language.

Other EME Temple, in Gujarat, India Elmore railway station, Australia Encrypted Media Extensions, a W3C specification Exempted Micro Enterprises